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Aqueous Humor pH in Experimental Eye Burns and Influence of Different Treatment Measures

Author: U. Lauz und H. W. Roth, H. Krey, B. Steinhardt

Journal: Albrecht v. Graefes Arch. klin. exp. Ophtal. 195, 33-40 (1975) [Article in German]

Abstract: 300 rabbit corneas were burned for – 1 minute by applying a filter paper of 10mm diameter soaked in different concentrations of NaOH. The aqueous humor pH was then measured at certain time intervals and after different treatment methods until the physiologic pH of 7.6 was reached. The results were statistically analyzed. Group 1, 2 and 3 were burned with 1N NaOH and 6N NaOH respectively without any treatment. In these groups, a “therapeutic” pH-level of 8.5 was measured on an average 0.5, 2.5 and 5 hours after the burn. Group 4 and 5 again were burned with 6N NaOH. In Group 4, the burn was followed by constant irrigation with physiologic saline by means of the Morgan Lens®. With this regimen, a pH of 8.5 was reached after 2.5 hours. In Group 5, the physiologic saline solution was replaced by a buffer solution (Isogutt®) and a pH of 8.5 was measured after only one hour. Based upon these results, it is felt that severe lye burns should be treated by constant irrigation with a buffer solution for several hours, a treatment that can easily be performed by use of the Morgan Lens.

The Oslo University Eye Department has used the Morgan Lens for 16 years.  We use it in all emergency cases and find that it gives the patients better chances than without this equipment.  In fact, we have reduced the need for hospitalization for more than one night for these patients, and the recovery without scars and permanent loss of visions is far better than without it.  Usually, we don't give our recommendations for products like this, but we have been so happy with the Morgan Lens that we would like to recommend it to all ophthalmologists.  Their patients will benefit from its use.

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MorTan Inc.

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Why Use The Morgan Lens?

The Morgan Lens is used in 90% of hospital emergency departments in the USA and can be inserted in less than 20 seconds. There simply is no other "hands-free" method of eye irrigation. Nothing else frees medical personnel to treat other injuries or to transport the patient while irrigation is underway. Nothing is more effective at treating ocular chemical, thermal, and actinic burns or removing non-embedded foreign bodies, even when the patient's eyes are closed tightly. Its design makes it simple and straightforward to use so minimal training is required.