Skip to the content

Ocular Irritancy Responses to Various pHs of Acids and Bases with and without Irrigation

Author: Murphy JC, Osterberg RE, Seabaugh VM, Bierbower GW

Journal: Toxicology 1982;23(4):281-91

Abstract: Acids and alkalis were instilled into the eyes of 2 groups of rabbits; the eyes of one group were washed with tap water 30 s after exposure. Damage seen in washed and unwashed eyes was not always related to pH. Some strong acids with greater acidity than pH 2.5 produced opacities while 0.3% hydrochloric acid with a pH of 1.28 produced no ocular damage. Phenol (5%) and acetic acid (5%) with pHs greater than 2.5 produced damage equivalent to or greater than that produced by equal concentrations (w/v) of the mineral acids. All alkalis with pHs ranging from 11.5 to 13.5 produced opacities and other ocular damage of different degrees depending upon the alkali and its concentration. For example, low concentrations of some alkalis in the pH range from 11.3 to 12.8 produced no ocular changes. The duration of the corneal opacities produced by phenol, 1% sodium hydroxide, acetic acid and anhydrous sodium carbonate and the onset of corneal opacity produced by 5% sulfuric acid, the weak acids and 1% sodium hydroxide were reduced as a result of washing the test eyes 30 s after instillation of the test material. These data suggest that acidity and alkalinity of the test material are not the only factors to be considered in relation to a substances’ capacity to produce severe ocular injury. The concentration of the test chemical and its period of contact with the eye prior to washing are also important.

I just spent three hours in the ER.  The trip to the ER was precipitated by my getting a mixture of bleach, Mr. Clean and water in my left eye while scrubbing the soffits of the siding on my house.  Whilst in the ER, I had my eye irrigated twice with a 0.9% solution of NaCl using the Morgan Lens to facilitate the irrigation.  THANK YOU for creating the Morgan Lens.  My eye felt so much better after the second round of irrigation, and it did take two rounds before the pH level in my eye returned to normal.  I know companies always hear about the things that go wrong with their equipment.  I want you to know that your equipment did something wonderful, and I want you to know how very much I appreciate it.

Patient - Platteville, WI

MorTan Inc.

Mailing Address:
P.O. Box 8719
Missoula, MT 59807
U.S.A.

Shipping Address:
329 East Pine St
Missoula, MT 59802
U.S.A.

Toll-Free Telephone1-800-423-8659
Telephone: 406-728-2522
Fax: 
406-728-9332

Emailmortan@morganlens.com

Hours
Monday - Thursday
7:30 AM - 4:00 PM MT

Friday
8:00 - 1:00 PM MT 

Why Use The Morgan Lens?

The Morgan Lens is used in 90% of hospital emergency departments in the USA and can be inserted in less than 20 seconds. There simply is no other "hands-free" method of eye irrigation. Nothing else frees medical personnel to treat other injuries or to transport the patient while irrigation is underway. Nothing is more effective at treating ocular chemical, thermal, and actinic burns or removing non-embedded foreign bodies, even when the patient's eyes are closed tightly. Its design makes it simple and straightforward to use so minimal training is required.